Apple has released iTunes 10.4.1 earlier today. Apple says that this update has number of improvements.
Here is some improvements in iTunes 10.4.1
- Fixes a problem where the media keys on some third-party keyboards work inconsistently with iTunes
- Addresses issues with adding artwork to songs and videos
- Resolves an issue which may cause iTunes to become unresponsive when purchasing an HD movie
- Fixes a problem where iTunes may take longer than expected to open after waking your Mac from sleep
- Addresses issues with VoiceOver support
You can grab the update manually on Apple’s downloads page.